Bending and Base-Stacking Interactions in Double-Stranded DNA
نویسندگان
چکیده
منابع مشابه
Bending and Base-Stacking Interactions in Double-Stranded DNA
An elastic model for double-stranded polymers is constructed to study the recently observed DNA entropic elasticity, cooperative extensibility, and supercoiling property. With the introduction of a new structural parameter (the folding angle w), bending deformations of sugar-phosphate backbones, steric effects of nucleotide base pairs, and base-stacking interactions are considered. The comprehe...
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Simple expressions for the bending and the base-stacking energy of double-stranded semiflexible biopolymers (such as DNA and actin) are derived. The distribution of the folding angle between the two strands is obtained by solving a Schrödinger equation variationally. Theoretical results based on this model on the extension versus force and extension versus degree of supercoiling relations of DN...
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ژورنال
عنوان ژورنال: Physical Review Letters
سال: 1999
ISSN: 0031-9007,1079-7114
DOI: 10.1103/physrevlett.82.4560